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Apoptotic Lymphocytes of H. sapiens Lose Nucleosomes in GC-Rich Promoters

We analyzed two sets of human CD4(+) nucleosomal DNA directly sequenced by Illumina (Solexa) high throughput sequencing method. The first set has ∼40 M sequences and was produced from the normal CD4+ T lymphocytes by micrococcal nuclease. The second set has ∼44 M sequences and was obtained from peri...

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Autors principals: Hosid, Sergey, Ioshikhes, Ilya
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117428/
https://ncbi.nlm.nih.gov/pubmed/25077608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003760
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