Specific-locus test shows ethylnitrosourea to be the most potent mutagen in the mouse.

Use of the specific-locus test to measure the frequency of transmitted gene mutations induced in mouse spermatogonia has shown ethylnitrosourea to be by far the most potent mutagen yet discovered in the mouse. The dose used, 250 mg/kg, gave a mutation rate 5 times as high as had been obtained with 6...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Russell, W L, Kelly, E M, Hunsicker, P R, Bangham, J W, Maddux, S C, Phipps, E L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1979
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411742/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/293686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.11.5818
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