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iPSC-derived neurons as a higher-throughput readout for autism: Promises and pitfalls

The elucidation of disease etiologies and establishment of robust, scalable, high-throughput screening assays for autism spectrum disorders (ASDs) have been impeded by both inaccessibility of disease-relevant neuronal tissue and the genetic heterogeneity of the disorder. Neuronal cells derived from...

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Detalhes bibliográficos
Main Authors: Prilutsky, Daria, Palmer, Nathan P., Smedemark-Margulies, Niklas, Schlaeger, Thorsten M., Margulies, David M., Kohane, Isaac S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117413/
https://ncbi.nlm.nih.gov/pubmed/24374161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2013.11.004
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