Isolation and characterization of pokeweed antiviral protein mutations in Saccharomyces cerevisiae: identification of residues important for toxicity.

Pokeweed antiviral protein (PAP), a 29-kDa protein isolated from Phytolacca americana inhibits translation by catalytically removing a specific adenine residue from the 28S rRNA of eukaryotic ribosomes. PAP has potent antiviral activity against many plant and animal viruses, including human immunode...

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出版年:	Proc Natl Acad Sci U S A
主要な著者:	Hur, Y, Hwang, D J, Zoubenko, O, Coetzer, C, Uckun, F M, Tumer, N E
フォーマット:	Artigo
言語:	Inglês
出版事項:	National Academy of Sciences 1995
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41174/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7667309/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8448
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Isolation and characterization of pokeweed antiviral protein mutations in Saccharomyces cerevisiae: identification of residues important for toxicity.

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