Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis

OBJECTIVE: To identify factors influencing age at symptom onset and disease course in autosomal dominant Alzheimer disease (ADAD), and develop evidence-based criteria for predicting symptom onset in ADAD. METHODS: We have collected individual-level data on ages at symptom onset and death from 387 AD...

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Detalhes bibliográficos
Main Authors: Ryman, Davis C., Acosta-Baena, Natalia, Aisen, Paul S., Bird, Thomas, Danek, Adrian, Fox, Nick C., Goate, Alison, Frommelt, Peter, Ghetti, Bernardino, Langbaum, Jessica B.S., Lopera, Francisco, Martins, Ralph, Masters, Colin L., Mayeux, Richard P., McDade, Eric, Moreno, Sonia, Reiman, Eric M., Ringman, John M., Salloway, Steve, Schofield, Peter R., Sperling, Reisa, Tariot, Pierre N., Xiong, Chengjie, Morris, John C., Bateman, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117367/
https://ncbi.nlm.nih.gov/pubmed/24928124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000596
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