Genetic variation in MTNR1B is associated with gestational diabetes mellitus and contributes only to the absolute level of beta cell compensation in Mexican Americans

AIMS/HYPOTHESIS: MTNR1B is a type 2 diabetes susceptibility locus associated with cross-sectional measures of insulin secretion. We hypothesised that variation in MTNR1B contributes to the absolute level of a diabetes-related trait, temporal rate of change in that trait, or both. METHODS: We tested...

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Main Authors: Ren, Jie, Xiang, Anny H., Trigo, Enrique, Takayanagi, Miwa, Beale, Elizabeth, Lawrence, Jean M., Hartiala, Jaana, Richey, Joyce M., Allayee, Hooman, Buchanan, Thomas A., Watanabe, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117246/
https://ncbi.nlm.nih.gov/pubmed/24728128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3239-3
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