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Epidermal growth factor stimulation of DNA synthesis is potentiated by compounds that inhibit its clustering in coated pits

We have used inhibitors of receptor-mediated endocytosis to investigate the mechanism and function of epidermal growth factor uptake by cultured cells. When rhodamine-labeled epidermal growth factor is bound to cell surface receptors on confluent monolayers of BALB/c 3T3 cells, it rapidly collects i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maxfield, Frederick R., Davies, Peter J. A., Klempner, Lev, Willingham, Mark C., Pastan, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1979
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC411724/
https://ncbi.nlm.nih.gov/pubmed/42903
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