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Single-molecule sequencing of an individual human genome
Recent advances in high-throughput DNA sequencing technologies have enabled order-of-magnitude improvements in both cost and throughput. Here we report the use of single-molecule methods to sequence an individual human genome. We aligned billions of 24- to 70-bp reads (32 bp average) to ~90% of the...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117198/ https://ncbi.nlm.nih.gov/pubmed/19668243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1561 |
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