The mechanism of action of phenylalanine ammonia-lyase: the role of prosthetic dehydroalanine.
Phenylalanine ammonia-lyase (EC 4.3.1.5) from parsley is posttranslationally modified by dehydrating its Ser-202 to the catalytically essential dehydroalanine prosthetic group. The codon of Ser-202 was changed to those of alanine and threonine by site-directed mutagenesis. These mutants and the reco...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41171/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7667307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.18.8433 |
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