Gene-based therapy of Parkinson’s Disease: Translation from animal model to human clinical trial employing convection enhanced delivery

The existing treatment of Parkinson’s disease (PD) is directed towards substituting dopamine loss with either dopamine replacement therapy or pharmacological therapies aimed at increasing dopamine at the synapse level. Emerging viable alternatives include the use of cell-based and gene-based therape...

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Bibliografske podrobnosti
Main Authors: Miranpuri, Gurwattan S., Kumbier, Lauren, Hinchman, Angelica, Schomberg, Dominic, Wang, Anyi, Marshall, Hope, Kubota, Ken, Ross, Chris, Sillay, Karl
Format: Artigo
Jezik:Inglês
Izdano: Indian Academy of Neurosciences 2012
Teme:
Comprehensive Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117084/
https://ncbi.nlm.nih.gov/pubmed/25205986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5214/ans.0972.7531.190310
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