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Structural and Temporal Requirements of Wnt/PCP Protein Vangl2 Function for Convergence and Extension Movements and Facial Branchiomotor Neuron Migration in Zebrafish

Van gogh-like 2 (Vangl2), a core component of the Wnt/Planar Cell Polarity (PCP) signaling pathway, is a four-pass transmembrane protein with N-terminal and C-terminal domains located in the cytosol, and is structurally conserved from flies to mammals. In vertebrates, Vangl2 plays an essential role...

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Detalhes bibliográficos
Main Authors: Pan, Xiufang, Sittaramane, Vinoth, Gurung, Suman, Chandrasekhar, Anand
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116749/
https://ncbi.nlm.nih.gov/pubmed/24333599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2013.12.001
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