Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Activation of EGFR signaling pathway leads to prostate cancer bone metastasis; however, therapies targeting EGFR have demonstrated limited effectiveness and led to drug resistance. miR-203 levels are down-regulated in clinical samples of primary prostate cancer and further reduced in metastatic pros...

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Bibliographische Detailangaben
Hauptverfasser: Siu, Man Kit, Abou-Kheir, Wassim, Yin, Juan Juan, Chang, Yung-Sheng, Barrett, Ben, Suau, Florent, Casey, Orla, Chen, Wei-Yu, Fang, Lei, Hynes, Paul, Hsieh, Yao-Yu, Liu, Yen-Nien, Huang, Jiaoti, Kelly, Kathleen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2014
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116519/
https://ncbi.nlm.nih.gov/pubmed/25004126
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