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Differences in heterocycle basicity distinguish homocysteine from cysteine using aldehyde-bearing fluorophores

We report the detection of homocysteine over cysteine based upon characteristic differences between 5-and 6-membered heterocyclic amines formed upon reaction with aldehyde-bearing compounds. Homocysteine-derived thiazinane-4-carboxylic acids are more basic than cysteine-derived thiazolidines-4-carbo...

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Autors principals: Barve, Aabha, Lowry, Mark, Escobedo, Jorge O., Huynh, Katherine T., Hakuna, Lovemore, Strongin, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116490/
https://ncbi.nlm.nih.gov/pubmed/24930401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc03527e
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