Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle

The balance between mitochondrial fission and fusion is crucial for mitochondria to perform its normal cellular functions. We hypothesized that cigarette smoke (CS) disrupts this balance and enhances mitochondrial dysfunction in the airway. In nonasthmatic human airway smooth muscle (ASM) cells, CS...

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Bibliografiske detaljer
Main Authors: Aravamudan, Bharathi, Kiel, Alexander, Freeman, Michelle, Delmotte, Philippe, Thompson, Michael, Vassallo, Robert, Sieck, Gary C., Pabelick, Christina M., Prakash, Y. S.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116419/
https://ncbi.nlm.nih.gov/pubmed/24610934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00155.2013
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