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Monoclonal antibody directed to a B-cell antigen present in rats, mice, and humans.

Spleen cells from a LEW.AVN rat immunized with cells from an MNR rat were fused with mouse myeloma cells to produce hybrid cell lines. One of these hybridomas produced a monoclonal antibody that was cytotoxic for bone marrow-derived (B) but not thymus-derived (T) cells. The antigen defined by this a...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Gasser, D L, Winters, B A, Haas, J B, McKearn, T J, Kennett, R H
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1979
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/315563/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4636
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