Kinetochore–microtubule attachment throughout mitosis potentiated by the elongated stalk of the kinetochore kinesin CENP-E

Centromere protein E (CENP-E) is a highly elongated kinesin that transports pole-proximal chromosomes during congression in prometaphase. During metaphase, it facilitates kinetochore–microtubule end-on attachment required to achieve and maintain chromosome alignment. In vitro CENP-E can walk process...

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Bibliographic Details
Main Authors: Vitre, Benjamin, Gudimchuk, Nikita, Borda, Ranier, Kim, Yumi, Heuser, John E., Cleveland, Don W., Grishchuk, Ekaterina L.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116301/
https://ncbi.nlm.nih.gov/pubmed/24920822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-01-0698
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