Enhanced mitotic recombination in a ligase-defective mutant of the yeast Saccharomyces cerevisiae.

The temperature-sensitive Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase, and the DNA synthesized at the restrictive temperature contains many single-strand breaks. We find that holding a diploid homozygous for cdc9 at the restrictive temperature and then plating cells at...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Game, J C, Johnston, L H, von Borstel, R C
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1979
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/388447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4589
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