Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities

Tissue inhibitor of metalloproteinases-1 (TIMP-1) regulates the extracellular matrix turnover by inhibiting the proteolytic activity of matrix metalloproteinases (MMPs). TIMP-1 also displays MMP-independent activities that influence the behavior of various cell types including neuronal plasticity, b...

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Bibliographic Details
Main Authors: Thevenard, Jessica, Verzeaux, Laurie, Devy, Jerôme, Etique, Nicolas, Jeanne, Albin, Schneider, Christophe, Hachet, Cathy, Ferracci, Géraldine, David, Marion, Martiny, Laurent, Charpentier, Emmanuelle, Khrestchatisky, Michel, Rivera, Santiago, Dedieu, Stéphane, Emonard, Hervé
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116228/
https://ncbi.nlm.nih.gov/pubmed/25075518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103839
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