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Efficient synthesis of eudistomin U and evaluation of its cytotoxicity

Eudistomin U is a member of a subclass of naturally occurring indole alkaloids known as β-carbolines. These molecules are reported to have diverse biological activity and high binding affinity to DNA, which make them attractive targets for total synthesis. We describe an efficient, five-step synthes...

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Hlavní autoři: Roggero, Chad M., Giulietti, Jennifer M., Mulcahy, Seann P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116134/
https://ncbi.nlm.nih.gov/pubmed/24930832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.05.049
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