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Role for β-arrestin in mediating paradoxical β(2)AR and PAR(2) signaling in asthma
G protein-coupled receptors (GPCRs) utilize (at least) two signal transduction pathways to elicit cellular responses including the classic G protein-dependent, and the more recently discovered β-arrestin-dependent, signaling pathways. In human and murine models of asthma, agonist-activation of β(2)-...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4116123/ https://ncbi.nlm.nih.gov/pubmed/24907413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2014.03.007 |
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