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Characterization and regulation of reductase kinase, a protein kinase that modulates the enzymic activity of 3-hydroxy-3-methylglutaryl-coenzyme A reductase

The activity of rat liver 3-hydroxy-3-methylglutaryl-coenzyme A reductase [HMG-CoA reductase; mevalonate:NADP(+) oxidoreductase (CoA-acylating), EC 1.1.1.34] can be modulated in vitro by a phosphorylation-dephosphorylation reaction sequence. A microsomal reductase kinase catalyzes the phosphorylatio...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Beg, Zafarul H., Stonik, John A., Brewer, H. Bryan
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1979
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/291971/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.9.4375
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