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Efficient germ-line transmission obtained with transgene-free induced pluripotent stem cells
Induced pluripotent stem (iPS) cells hold great promise for regenerative medicine. To overcome potential problems associated with transgene insertions, efforts have been directed over the past several years to generate transgene-free iPS cells by using non-viral-vector approaches. To date, however,...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4115572/ https://ncbi.nlm.nih.gov/pubmed/25002522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409933111 |
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