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Production of transgenic rats by lentiviral transduction of male germ-line stem cells

Primary cultures of rat spermatogenic cells that did not bind to collagen matrices were able to colonize and form mature spermatozoa when transferred to testes of recipient males. Up to 73% of the progeny from matings with recipient males were derived from the transferred spermatogenic cells. Subseq...

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Main Authors: Hamra, F. Kent, Gatlin, Joel, Chapman, Karen M., Grellhesl, Dana M., Garcia, J. Victor, Hammer, Robert E., Garbers, David L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC137522/
https://ncbi.nlm.nih.gov/pubmed/12391306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.222561399
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