Mutation of a major CG methylase in rice causes genome-wide hypomethylation, dysregulated genome expression, and seedling lethality

Cytosine methylation at CG sites ((m)CG) plays critical roles in development, epigenetic inheritance, and genome stability in mammals and plants. In the dicot model plant Arabidopsis thaliana, methyltransferase 1 (MET1), a principal CG methylase, functions to maintain (m)CG during DNA replication, w...

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Detalhes bibliográficos
Main Authors: Hu, Lanjuan, Li, Ning, Xu, Chunming, Zhong, Silin, Lin, Xiuyun, Yang, Jingjing, Zhou, Tianqi, Yuliang, Anzhi, Wu, Ying, Chen, Yun-Ru, Cao, Xiaofeng, Zemach, Assaf, Rustgi, Sachin, von Wettstein, Diter, Liu, Bao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115543/
https://ncbi.nlm.nih.gov/pubmed/25002488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410761111
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