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Device design and materials optimization of conformal coating for islets of Langerhans

Encapsulation of islets of Langerhans may represent a way to transplant islets in the absence of immunosuppression. Traditional methods for encapsulation lead to diffusional limitations imposed by the size of the capsules (600–1,000 μm in diameter), which results in core hypoxia and delayed insulin...

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Autores principales: Tomei, Alice A., Manzoli, Vita, Fraker, Christopher A., Giraldo, Jaime, Velluto, Diana, Najjar, Mejdi, Pileggi, Antonello, Molano, R. Damaris, Ricordi, Camillo, Stabler, Cherie L., Hubbell, Jeffrey A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115512/
https://ncbi.nlm.nih.gov/pubmed/24982192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402216111
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