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Enamel matrix derivative protein enhances production of matrixmetalloproteinase-2 by osteoblasts

BACKGROUND: Matrix metalloproteinases (MMPs) degrade the extracellular matrix (ECM) and regulate remodeling and regeneration of bone. Enamel matrix derivative (EMD) protein has been used clinically for periodontal regeneration, although its molecular mechanisms are not clear. We evaluated the role o...

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Autori principali: Goda, Seiji, Inoue, Hiroshi, Takeuchi, Osamu, Ujii, Yosuke, Domae, Eisuke, Ikeo, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115475/
https://ncbi.nlm.nih.gov/pubmed/25011999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6831-14-85
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