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Plasma 8-hydroxy-2′-deoxyguanosine Levels in Huntington Disease and Healthy Controls Treated with Coenzyme Q10

We analyzed plasma 8OHdG concentrations in 20 individuals enrolled in the Pre-2CARE study before and after treatment with CoQ. Treatment resulted in a mean reduction in 8OHdG of 2.9 ± 2.9 pg/ml for the cohort (p = 0.0003) and 3.0 ± 2.6 pg/ml, for the HD group (p = 0.002). Baseline 8OHdG levels were...

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Detalhes bibliográficos
Main Authors: Biglan, K.M., Dorsey, E.R., Evans, R.V.V., Ross, C.A., Hersch, S., Shoulson, I., Matson, W., Kieburtz, K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115297/
https://ncbi.nlm.nih.gov/pubmed/25063191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JHD-2012-120007
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