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Analysis of Gene-Gene Interactions Using Gene-Trait Similarity Regression

OBJECTIVE: Gene-Gene interactions (GxG) are important to study because of their extensiveness in biological systems and their potential in explaining missing heritability of complex traits. In this work, we propose a new similarity-based test to assess GxG at gene level, which permits the study of e...

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Détails bibliographiques
Auteurs principaux: Wang, Xin, Epstein, Michael P., Tzeng, Jung-Ying
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115296/
https://ncbi.nlm.nih.gov/pubmed/24969398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360161
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