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Optimization of the Protocol for the Isolation and Refolding of the Extracellular Domain of HER2 Expressed in Escherichia coli

Receptor 2 of the human epidermal growth factor (HER2/neu, c-erbB2) is a 185 kDa proto-oncogene protein characterized by an overexpression in some oncological diseases, including 30% of mammary glands cancers, as well as tumors in the ovary, stomach and other organs of the human body. Since HER2- tu...

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Detalhes bibliográficos
Main Authors: Dolgikh, V. V., Senderskiy, I. V., Tetz, G. V., Tetz, V. V.
Formato: Artigo
Idioma:Inglês
Publicado em: A.I. Gordeyev 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4115232/
https://ncbi.nlm.nih.gov/pubmed/25093117
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