Antisense DNA downregulation of the ERBB2 oncogene measured by a flow cytometric assay.

A causal role has been inferred for ERBB2 overexpression in the etiology of breast cancer and other epithelial malignancies. The development of therapeutics that inhibit this tyrosine kinase cell surface receptor remains a high priority. This report describes the specific downregulation of ERBB2 pro...

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Bibliografiske detaljer
Main Authors: Vaughn, J P, Iglehart, J D, Demirdji, S, Davis, P, Babiss, L E, Caruthers, M H, Marks, J R
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41152/
https://ncbi.nlm.nih.gov/pubmed/7667291
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