Short Term Morphine Exposure In Vitro Alters Proliferation and Differentiation of Neural Progenitor Cells and Promotes Apoptosis via Mu Receptors

BACKGROUND: Chronic morphine treatment inhibits neural progenitor cell (NPC) progression and negatively effects hippocampal neurogenesis. However, the effect of acute opioid treatment on cell development and its influence on NPC differentiation and proliferation in vitro is unknown. We aim to invest...

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Bibliografiske detaljer
Main Authors: Willner, Dafna, Cohen-Yeshurun, Ayelet, Avidan, Alexander, Ozersky, Vladislav, Shohami, Esther, Leker, Ronen R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114742/
https://ncbi.nlm.nih.gov/pubmed/25072277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0103043
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