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Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome

The molecular link between proteinuria and hyperlipidemia in nephrotic syndrome is not known. We show in the present study that plasma angiopoietin-like 4 (Angptl4) links proteinuria with hypertriglyceridemia through two negative feedback loops. In previous studies in a rat model that mimics human m...

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Detalhes bibliográficos
Main Authors: Clement, Lionel C, Macé, Camille, Avila-Casado, Carmen, Joles, Jaap A, Kersten, Sander, Chugh, Sumant S
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114723/
https://ncbi.nlm.nih.gov/pubmed/24317117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3396
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