Entrapment of metaphase chromosomes into phospholipid vesicles (lipochromosomes): Carrier potential in gene transfer

Transfer of genes from one type of cultured mammalian cell to another by using isolated metaphase chromosomes has been reported with a frequency of one per 10(6)-10(8) cells. Very recently a rate of 16/10(6) has been reported with Chinese hamster ovary cells [Spandidos, D. A. & Siminovitch, L. (...

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Autori principali: Mukherjee, Anil B., Orloff, Sheldon, Butler, Jean DeB., Triche, Timothy, Lalley, Peter, Schulman, Joseph D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1978
Soggetti:
Biological Sciences: Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC411471/
https://ncbi.nlm.nih.gov/pubmed/349565
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