The antibacterial toxin colicin N binds to the inner core of lipopolysaccharide and close to its translocator protein

Colicins are a diverse family of large antibacterial protein toxins, secreted by and active against Escherichia coli and must cross their target cell's outer membrane barrier to kill. To achieve this, most colicins require an abundant porin (e.g. OmpF) plus a low‐copy‐number, high‐affinity, out...

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Bibliographic Details
Main Authors: Johnson, Christopher L., Ridley, Helen, Marchetti, Roberta, Silipo, Alba, Griffin, David C., Crawford, Lucy, Bonev, Boyan, Molinaro, Antonio, Lakey, Jeremy H.
Format: Artigo
Language:Inglês
Published: Blackwell Scientific Publications 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114557/
https://ncbi.nlm.nih.gov/pubmed/24589252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12568
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