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Defective regulation of cholesterol biosynthesis and plasma membrane fluidity in a Chinese hamster ovary cell mutant.

A Chinese hamster ovary cell mutant resistant to killing by 25-hydroxycholesterol is shown to be defective in the regulation of cholesterol synthesis by exogenous cholesterol. When grown with various cholesterol supplements in delipidized serum, the mutant cell exhibits a variation in cholesterol co...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Sinensky, M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411447/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/274716/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.3.1247
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