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Early Life Stress Triggers Persistent Colonic Barrier Dysfunction and Exacerbates Colitis in Adult IL-10(-/-) Mice

BACKGROUND: It has become increasingly evident that disease flares in the human inflammatory bowel diseases (IBD) are influenced by life stress. It is known that life stress can trigger disturbances in intestinal barrier function and activate proinflammatory signaling pathways, which are important c...

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Detalhes bibliográficos
Main Authors: Lennon, E.M., Maharshak, N., Elloumi, H., Borst, L., Plevy, S.E., Moeser, A.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114389/
https://ncbi.nlm.nih.gov/pubmed/23446335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e3182802a4e
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