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Protein Product of CLN6 Gene Responsible for Variant Late-Onset Infantile Neuronal Ceroid Lipofuscinosis Interacts with CRMP-2

Mutations in CLN6 cause variant late-onset neuronal ceroid lipofuscinosis (vLINCL), a childhood neurodegenerative disorder resulting from aberrant neuronal cell loss and pathological accumulation of lysosomal auto-fluorescent storage material in the central nervous system. The direct function of the...

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Bibliografiske detaljer
Main Authors: Benedict, Jared W., Getty, Amanda L., Wishart, Thomas M., Gillingwater, Thomas H., Pearce, David A.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113904/
https://ncbi.nlm.nih.gov/pubmed/19235893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22032
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