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The immunomodulator AS101suppresses production of inflammatory cytokines and ameliorates the pathogenesis of experimental autoimmune encephalomyelitis

We reported that AS101 (organotellurium compound, trichloro(dioxoethylene-O,O′) tellurate) inhibited the differentiation of Th17 cells and reduced the production of IL-17 and GM-CSF. In addition, AS101 promoted the production of IL-2 in activated T cells. Flow cytometric analysis showed that AS101 i...

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Autori principali: Xie, Li, Chen, Jing, McMickle, Anthony, Awar, Nadia, Nady, Soad, Sredni, Benjamin, Drew, Paul D., Yu, Shiguang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113726/
https://ncbi.nlm.nih.gov/pubmed/24975323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.05.015
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