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Characterizing the initial encounter complex in cadherin adhesion
Cadherins are Ca(2+)-dependent cell-cell adhesion proteins with an extracellular region of five domains (EC1 to EC5). Adhesion is mediated by “strand-swapping” of a conserved tryptophan residue in position 2 between EC1 domains of opposing cadherins, but the formation of this structure is not well u...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4113602/ https://ncbi.nlm.nih.gov/pubmed/19646884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.012 |
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