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Characterizing the initial encounter complex in cadherin adhesion

Cadherins are Ca(2+)-dependent cell-cell adhesion proteins with an extracellular region of five domains (EC1 to EC5). Adhesion is mediated by “strand-swapping” of a conserved tryptophan residue in position 2 between EC1 domains of opposing cadherins, but the formation of this structure is not well u...

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Autors principals: Sivasankar, Sanjeevi, Zhang, Yunxiang, Nelson, W. James, Chu, Steven
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113602/
https://ncbi.nlm.nih.gov/pubmed/19646884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.06.012
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