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Lopinavir inhibits insulin signaling by promoting protein tyrosine phosphatase 1B expression

Treatment with antiretroviral therapy, including protease inhibitors (PIs), may result in metabolic side-effects, for example insulin resistance. The aim of the present study was to investigate the mechanism of the dysregulation of insulin signaling by two PIs, lopinavir and darunavir, by analyzing...

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Detalhes bibliográficos
Main Authors: KITAZAWA, TAKATOSHI, YOSHINO, YUSUKE, SUZUKI, SATOSHI, KOGA, ICHIRO, OTA, YASUO
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113574/
https://ncbi.nlm.nih.gov/pubmed/25120613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2014.1826
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