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Repair of depurinated DNA in vitro by enzymes purified from human lymphoblasts.

Alkali-labile lesions introduced into T7 DNA by treatment with methyl methanesulfonate were removed and the DNA was repaired by incubation with DNA polymerase alpha and nuclease from a human lymphoblastoid line followed by the addition of DNA ligase. The nuclease preparation contains both apurinic e...

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Autors principals: Bose, K, Karran, P, Strauss, B
Format: Artigo
Idioma:Inglês
Publicat: 1978
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC411343/
https://ncbi.nlm.nih.gov/pubmed/273243
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