Regulation of protein synthesis in rabbit reticulocyte lysates by the heme-regulated protein kinase: Inhibition of interaction of Met-tRNA(f)(Met) binding factor with another initiation factor in formation of Met-tRNA(f)(Met)·40S ribosomal subunit complexes

Protein synthesis in reticulocytes and their lysates is regulated by heme. In heme deficiency a heme-regulated translational inhibitor (HRI) that blocks initiation of polypeptide chains is activated. HRI is a protein kinase (ATP: protein phosphotransferase, EC 2.7.1.37) that specifically phosphoryla...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Ranu, R. S., London, I. M., Das, A., Dasgupta, A., Majumdar, A., Ralston, R., Roy, R., Gupta, N. K.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1978
Assuntos:
Biological Sciences: Biochemistry
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/273238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.2.745
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