Antibody-mediated activation of a defective beta-D-galactosidase: dimeric form of the activatable mutant enzyme.

Sedimentation analyses of AMEF, an activatable mutant beta-D-galactosidase (beta-D-galactoside galactohydrolase, EC 3.2.1.23), and the products of its reaction with Fab fragments of activating antibody show that this enzyme exists mainly as 10S dimers. Activation of AMEF by purified antibody resulte...

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Detalles Bibliográficos
Main Authors: de Macario, E C, Ellis, J, Guzman, R, Rotman, B
Formato: Artigo
Idioma:Inglês
Publicado: 1978
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC411328/
https://ncbi.nlm.nih.gov/pubmed/416439
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