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Haploinsufficiency of insulin gene enhancer protein 1 (ISL1) is associated with d-transposition of the great arteries

Congenital heart defects are the most common malformation, and are the foremost causes of mortality in the first year of life. Among congenital heart defects, conotruncal defects represent about 20% and are severe malformations with significant morbidity. Insulin gene enhancer protein 1 (ISL1) has b...

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Main Authors: Osoegawa, Kazutoyo, Schultz, Kathleen, Yun, Kenneth, Mohammed, Nebil, Shaw, Gary M, Lammer, Edward J
Formato: Artigo
Idioma:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113275/
https://ncbi.nlm.nih.gov/pubmed/25077177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.75
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