Leptin signaling in GFAP-expressing adult glia cells regulates hypothalamic neuronal circuits and feeding

We have shown that synaptic re-organization of hypothalamic feeding circuits in response to metabolic shifts involves astrocytes, cells that can directly respond to the metabolic hormone, leptin, in vitro. It is not known whether the role of glia cells in hypothalamic synaptic adaptions is active or...

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Detalhes bibliográficos
Main Authors: Kim1, Jae Geun, Suyama, Shigetomo, Koch, Marco, Jin, Sungho, Argente-Arizon, Pilar, Argente, Jesus, Liu, Zhong-Wu, Zimmer, Marcelo R., Jeong, Jin Kwon, Szigeti-Buck, Klara, Gao, Yuanqing, Garcia-Caceres, Cristina, Yi, Chun-Xia, Salmaso, Natalina, Vaccarino, Flora M., Chowen, Julie, Diano, Sabrina, Dietrich, Marcelo O, Tschöp, Matthias H., Horvath, Tamas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113214/
https://ncbi.nlm.nih.gov/pubmed/24880214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3725
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