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Bidirectional, Optical Sign-Dependent Regulation of BMP2 Gene Expression in Chick Retinal Pigment Epithelium

PURPOSE. We explored the role of bone morphogenic protein 2 (BMP2) in defocus-induced ocular growth using gene expression changes in RPE as a surrogate. METHODS. Young White-Leghorn chickens were used in this study. Normal gene expression of BMP2 and its receptors was examined in retina, RPE, and ch...

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Detalhes bibliográficos
Main Authors: Zhang, Yan, Liu, Yue, Wildsoet, Christine F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113186/
https://ncbi.nlm.nih.gov/pubmed/22879416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9917
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