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Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice

BACKGROUND: Central nervous system (CNS) trauma and neurodegenerative disorders trigger a cascade of cellular and molecular events resulting in neuronal apoptosis and regenerative failure. The pathogenic mechanisms and gene expression changes associated with these detrimental events can be effective...

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Autors principals: Sharma, Tasneem P, McDowell, Colleen M, Liu, Yang, Wagner, Alex H, Thole, David, Faga, Benjamin P, Wordinger, Robert J, Braun, Terry A, Clark, Abbot F
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113182/
https://ncbi.nlm.nih.gov/pubmed/24767545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-14
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