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Translational control: recognition of the methylated 5' end and an internal sequence in eukaryotic mRNA by the initiation factor that binds methionyl-tRNAfMet.

Structural analogs of the methylated 5' end (cap) of eukaryotic mRNA, such as 7-methylguanosine 5'-monophosphate, specifically inhibit both GTP-dependent binding of Met-tRNAfMet and binding of globin mRNA to eukaryotic initiation factor 2 (eIF-2). Addition of purified eIF-2 effectively rel...

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Bibliografske podrobnosti
Main Authors: Kaempfer, R, Rosen, H, Israeli, R
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC411313/
https://ncbi.nlm.nih.gov/pubmed/273228
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