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Protein Aggregation Behavior Regulates Cyclin Transcript Localization and Cell-Cycle Control

Little is known about the active positioning of transcripts outside of embryogenesis or highly polarized cells. We show here that a specific G1 cyclin transcript is highly clustered in the cytoplasm of large multinucleate cells. This heterogeneous cyclin transcript localization results from aggregat...

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Detalhes bibliográficos
Main Authors: Lee, ChangHwan, Zhang, Huaiying, Baker, Amy E., Occhipinti, Patricia, Borsuk, Mark E., Gladfelter, Amy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113091/
https://ncbi.nlm.nih.gov/pubmed/23769973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.007
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