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Early Life Exposure to Maternal Insulin Resistance Has Persistent Effects on Hepatic NAFLD in Juvenile Nonhuman Primates

The origins of nonalcoholic fatty liver disease (NAFLD) may lie in early intrauterine exposures. Here we examined the maternal response to chronic maternal high-fat (HF) diet and the impact of postweaning healthy diet on mechanisms for NAFLD development in juvenile nonhuman primate (NHP) offspring a...

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Autors principals: Thorn, Stephanie R., Baquero, Karalee C., Newsom, Sean A., El Kasmi, Karim C., Bergman, Bryan C., Shulman, Gerald I., Grove, Kevin L., Friedman, Jacob E.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4113070/
https://ncbi.nlm.nih.gov/pubmed/24705404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0276
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